Dr Johan Van Hove

Biography

Dr. Van Hove received his medical education and his training in pediatrics at the Catholic University Leuven in Belgium. He did a fellowship in clinical and biochemical genetics at Duke University Medical Center, Durham, NC, USA. He obtained his PhD from the University in Leuven. He spent time in Australia where he learned mitochondrial diseases. He worked from 1998 to 2003 in Leuven. Since 2003 he has been at the University of Colorado and Children’s Hospital Colorado. His research interests include disorders of cellular energetics as part of the Mitochondrial Center in Colorado. This research focuses on diagnostic studies with application on new disorders, and use for evaluation of new therapies.

His other research interest includes neurometabolic disorders in particular disorders of glycine metabolism. He has been studying nonketotic hyperglycinemia for over 30 years. He has studied the clinical spectrum, radiologic features, the genetic basis, and the optimization of current treatments of benzoate and ketogenic diet. Current studies focus on mouse models to studying the biochemistry and develop new treatments. In clinic, studies focus on optimizing current treatment and a natural history study aimed at clinical trial preparedness.